Tīmeklis2003. gada 1. apr. · In summary, decalin inhalation exposure from 25 to 400 ppm for up to 13 weeks clearly induced male rat-specific α 2u-globulin nephropathy. Both decalin and 2-decalone accumulated in the male kidneys but not in female rat kidneys along with α 2u-globulin, suggesting that one or both of these compounds may bind to the … TīmeklisBackground: alpha 2u-Globulin. alpha 2u -Globulin, also known as PGCL1, is a member of the Lipocalin family that show 87-98% amino acid sequence identity. alpha 2u -Globulin is the major urinary protein excreted by adult male rat. It is expressed at highest levels in male liver and coagulate glands.
Streptozotocin induces alpha-2u globulin nephropathy in male rats ...
Tīmeklisterisation of alpha 2u-globulin nephropathy in male rats has also been discussed for decades [1–6, 8, 12, 13]. Sev-eral chemicals and drugs have been demonstrated to in-duce alpha 2u-globulin nephropathy only in mature male rats in association with neoplasia enhancement. Alpha 2u-globulin is synthesised in the liver under the Tīmeklis1991. gada 1. maijs · The NCI-Black-Reiter (NBR) rat is the only strain of male rat known not to synthesize the hepatic form of the low molecular weight protein, α 2u-globulin.In previous studies, NBR rats were shown not to develop renal disease when exposed to decalin, a compound known to induce α 2u-globulin nephropathy in other … scrubbed house scrubbed soul
Protection of spermatogenesis by α 2u globulin in rats treated …
Tīmeklis2015. gada 22. febr. · ResponseFormat=WebMessageFormat.Json] In my controller to return back a simple poco I'm using a JsonResult as the return type, and creating the … TīmeklisIn a study in rats, this particular male-specific tendency correlated with increased renal expression of a small molecular weight drug-binding protein, alpha 2u-globulin. Male … Tīmeklis2001. gada 11. maijs · α 2u-Globulin (a2uG), expressed primarily in the mature male rat liver and excreted in the urine (Roy and Neuhaus, 1966a, Roy and Neuhaus, 1966b), … pch search win login