Ctcf和ctcfl

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August undefined, 2024

WebWidespread expression of BORIS/CTCFL in normal and cancer cells. BORIS (CTCFL) is the paralog of CTCF (CCCTC-binding factor; NM_006565), a ubiquitously expressed …

Widespread expression of BORIS/CTCFL in normal and cancer cells

WebAlthough CTCF cKO and control mice started the training with a similar level of correct responses, CTCF cKO mice displayed a learning decit as training proceeded and did not reach the same level Fig. 1 Touch screen analysis of behavioral phenotypes showed cognitive impairments in CTCF cKO mice. a PD reversal accuracy (i.e., correct WebMay 11, 2024 · In line with these differences, CTCF and CTCFL have very different expression profiles: CTCF is present in all cell types, while in contrast CTCFL is normally … chinthurst school holiday dates

Anti-CTCF Antibody 07-729 - Merck Millipore

WebCTCF is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms CTCF - What does CTCF stand for? The Free Dictionary WebCTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is normally transiently … WebOct 8, 2024 · By PCR screening a testis cDNA library for CTCF-like sequences, followed by 5-prime RACE, Loukinov et al. (2002) isolated a cDNA encoding CTCFL, which they … granny\\u0027s quilting shapes

Anti-CTCF Antibody serum, Upstate® Sigma-Aldrich

WebMay 11, 2024 · Ubiquitously expressed CTCF is involved in numerous cellular functions, such as organizing chromatin into TAD structures. In contrast, its paralog, CTCFL, is normally only present in the testis. However, it is also aberrantly expressed in many cancers. While it is known that shared and unique zinc finger sequences in CTCF and CTCFL … Web5.1 CTCF genome organizer and the cohesin complex. CTCF (CCCTC-binding factor) is a multiple zinc finger protein that exerts diversified functions under different genomic contexts. CTCF was first isolated and cloned on the basis of its ability to bind to highly divergent 50–60 bp sequences within the promoter region of the chicken Myc gene ... granny\u0027s pumpkin roll recipeWebApr 4, 2024 · Title: CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming. Myotonic dystrophy type 1 … granny\\u0027s pumpkin roll recipe

"WebCTCFL Antibodies. Antibodies that detect CTCFL can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, … " - Ctcf和ctcfl

Ctcf和ctcfl

Web我们为您找到 ctcf 的 1 个相关产品结果。 ... 生命科学基础与转化研究的主要领域，包括细胞生物学、肿瘤、免疫与炎症、表观遗传学和转录调控、代谢与内分泌、衰老、心血管、干细胞和发育、神经科学、蛋白质翻译后修饰等，还提供病理学研究与伴随诊断 ... WebJun 18, 2012 · CTCFL acts as a male germ cell gene regulator, preferably binding near promoters with active chromatin marks. Interestingly, CTCF and CTCFL bind a highly …

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WebApr 1, 2024 · CTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is … WebMay 11, 2024 · CTCFL and CTCF-CTCFL overlapping binding sites are frequently bound by both CLC and LCL (Fig. 4 d, e), but at some locations, fusion protein peaks are reduced in size compared to that of CTCFL (e.g., at Ctcfl, Prss50, Gal3st1 loci) (Fig. 4 d). Sites bound by CTCF only were preferentially bound by LCL as opposed to CLC (Fig. 4 f).

WebAnti-CTCF Antibody serum, Upstate®; Synonyms: 11 zinc finger transcriptional repressor, 11-zinc finger protein, CCCTC-binding factor, CCCTC-binding factor (zinc finger protein), CTCFL paralog, transcriptional repressor CTCF; find Sigma-Aldrich-07729 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich WebNov 5, 2024 · The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner. Epigenetics Chromatin 5 , 8 (2012).

WebCTCF常常位于TAD和loop的边界，起到“隔离子”的作用。近年来提出的loop extrusion模型也认为CTCF和cohesin的协调作用是loop形成的普遍机理。然而，虽然有了假设，人们却一直不清楚CTCF是如何作用于染色质，并 … WebChIPAb+ CTCF - ChIP Validated Antibody and Primer Set clone 1.2.1.5.4, from mouse; Synonyms: 11 zinc finger transcriptional repressor, 11-zinc finger protein, CCCTC-binding factor, CCCTC-binding factor (zinc finger protein), CTCFL paralog, transcriptional repressor CTCF; find Sigma-Aldrich-1710044 MSDS, related peer-reviewed papers, technical …

WebOct 7, 2014 · Thus, the comparison between CTCF and CTCFL domains revealed that only CTCF harbours the powerful chromatin opening domain within the N-terminus plus zinc finger region. Chromatin opening is usually associated with, or is caused by, histone modifications. Since we found the closed array of the F42B8 cells to be devoid of active …

WebStatistical differences between individual binding categories (CTCFL, CTCF/CTCFL co-bound and CTCF or CTCFL stand-alone sites) and the average CTCF site as reference were calculated by Wilcoxon signed rank test (two-sided alternative: ‘binding in analyzed category is greater than that of CTCF binding’). The corresponding code is available ... chinthurst school postcodeWebU25435 - Human transcriptional repressor (CTCF) mRNA, complete cds. BC130486 - Homo sapiens CCCTC-binding factor (zinc finger protein)-like, mRNA (cDNA clone MGC:163358 IMAGE:40146517), complete cds. DQ294738 - Homo sapiens BORIS-like protein (CTCFL) mRNA, complete cds, alternatively spliced. BC014267 - Homo sapiens CCCTC-binding … chinthurst school staff listWebApr 1, 2024 · CTCF and CTCFL contain N-terminal and C-terminal domains and a central 11-zinc finger region. CTCF binds to approximately 80 000 sites on mammalian chromosomes [33,34] through a subset of its eleven zinc fingers (ZFs). The ZFs of CTCFL and CTCF have significant homology with the ZFs of CTCF (74.1%), but the N-terminal … granny\\u0027s quilting shapes north carolinaWebApr 1, 2024 · CTCFL binds to a very similar sequence than CTCF and, if expressed at higher levels, as it does in many cancers, could compete with CTCF for binding at a subset of sites [51, 52]. Since CTCFL lacks the domain required for cohesin interaction, this protein is unable to stop cohesin extrusion and to form stable loops between distant sites in the ... chinthurst school staffWebCTCFL paralog; transcriptional repressor CTCF; Background Information: CTCF is a ubiquitous 11 zinc finger (ZF) protein with highly versatile functions. A transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene. It also binds to the PLK and PIM1 promoters. CTCF may prevent the access of transcriptional activators to enhancers. granny\\u0027s quilt shop dickson tnWebNov 30, 2010 · Function. Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by … chinthurst school policiesWebctcf和共有序列ccgcgnggnggcag相結合。這條序列在其結構域中有11個鋅指結構。ctcf和基因的結合被cpg的甲基化所影響。 ctcf在19個細胞系中大約有55000個共同的dna結合位 … granny\\u0027s purse book