WebApr 12, 2024 · (F and G) Shown are UMAPs visualizing CD8 + T cell populations in CyTOF datasets for non–small cell lung cancer (NSCLC) or LUAD (F) and GBM (G). ( H and I ) Shown is the network topology of SKCM (H) and GBM (I) scRNA-seq–based CellPhoneDB interaction predictions, filtered on the basis of TCGA tumor bulk RNA-seq data … WebDec 25, 2024 · Cisplatin treatment reduced tumor growth, number of lung metastasis, and the splenomegaly of 4T1 tumor bearing mice. We showed that cisplatin inhibited …
Biodistribution of cisplatin revealed by imaging mass ... - Nature
WebDescription. Potent pro-apoptotic anticancer agent; activates caspase-3. Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and … WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 … tsm reginald investment
Cell-ID Cisplatin - Imaging Mass Cytometry and Mass …
WebCisplatin uptake and effects on proliferation BxPC-3 pancreatic cancer cells and ME-180 cervical cancer cells exposed to cisplatin in vitro were pulse-labeled with 10 mM IdU for 30 min and analyzed for platinum and iodine content by mass cytometry. Figure 1a illustrates single cell measurements taken from control and cisplatin-treated cells ... WebMay 17, 2024 · We developed a 40+ parameter CyTOF panel and demonstrate that compared to flow cytometry, CyTOF yields analogous quantification of cell lineages … WebCisplatin is ideally detected in the 195Pt channel of the CyTOF® system. PBMC were incubated for three days in media alone (left) or with PHA (right). Cells were then stained … tsm reps離開